🚨 Common Vape Ingredients Found to Deform Fetal Skulls in Mice — Even Without Nicotine

A new study from The Ohio State University has revealed that nicotine-free vape liquids may still pose serious risks during pregnancy. Led by anatomist Dr. James Cray, researchers exposed pregnant mice to the base ingredients found in most vape juices—propylene glycol and glycerol—without adding nicotine or flavorings.

The findings were alarming. Offspring showed smaller, narrower skulls, shorter facial bones, and lower body weight compared to control groups. Notably, the blend with 30/70 propylene glycol to glycerol—often marketed as a “smoother” or “safer” vape base—caused the most significant abnormalities in craniofacial development.

While the study does not directly translate to human outcomes, it challenges the widespread assumption that vaping without nicotine is safe—particularly for pregnant individuals. With little regulation on vape ingredients and limited research on their long-term effects, the study underscores a critical public health concern: every component in a vape, not just nicotine, deserves scrutiny.

The authors call for greater awareness and more research, especially considering the growing popularity of vaping among young adults and pregnant users.

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